We recommend what we believe is the most effective dosage for most people.
Currently, no one can be sure what that is.
Based on studies with IV of NMN and NAD+ where 100% is injected directly into the bloodstream, 400-600 mg is not too much for a human.
IV clinics like ours use 700 mg per day with fantastic results. You will get 5-10x more NMN direct to the blood vs a capsule that is mostly degraded to NAM, but NMN or NAD+ in the blood is not a problem.
The problem is, getting too much NAM.
As demonstrated in a recent fertility study by Dr. Wu, the human equivalent of 400 mg per day was great, 1600 mg per day was not good.
That is from the excess NAM created from oral dosing, not from NMN in the bloodstream.